May 06, · Sickle cell anemia is a disorder of the blood that is caused by the inheritance of the gene that alters the shape of the sickle cell. Therefore, the gene interferes with the working of hemoglobin in the movement of oxygen. The prevalence of the sickle cell anemia varies regarding the geographical position and the ethnic identity Apr 10, · Sickle Cell Anemia Essay. Sickle cell anemia is a genetic blood disorder which is inherited from both parents, that causes red blood cells in patients to be sickle -shaped. This causes the red blood cells to clump together, and be unable to retain oxygen Essay on Sickle Cell Anemia Words | 11 Pages. Abstract Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body. A gene causes the bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia
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For example, in the case of sickle beta thalassemia, the individual has inherited a gene for hemoglobin S. from one parent and a gene for beta-thalassemia from the other. Or, in the instance of SC disease, the individual has inherited a gene for hemoglobin S. from one parent and a gene for hemoglobin C. from the other. The sickle cell trait in heterozygous carriers confers the resistance to malaria phenotype characterized by a dominant gene Sickle cell anemia, Wikipedia.
ecause people with sickle trait were more likely to survive malaria outbreaks in Africa than those with normal hemoglobin, it is believed that sickle hemoglobin evolved as a protection against malaria. Haplotypes of sickle cell disease are polymorphic restriction endonuclease sites in and around the mutant beta-globin gene Acording to Fieldsthe existence of haplotypes specific to certain regions of the world suggests that the mutant beta globin gene arose….
Bibliography Ashley-Koch, A. And Olney, R. Sickle hemoglobin Hb S allele and sickle cell disease. American Journal of Genetics 9 : Fields, E. Phenotypic variation in sickle cell disease: An analysis. Harvard University. html Genetic disease profile: Sickle cell anemia. shtml How does sickle cell cause disease? These crises are a direct result of way in which the deformed red blood cells adhere to both each other and the insides of the blood vessel walls, blocking tissues from receiving oxygen.
The disease is prevalent across some parts of Africa, the Middle East and India, which is due to the way in which the heterozygous form of the condition offers carriers a degree of protection against malaria, which is present in these areas.
As a result, there is also a significant incidence of the disease in African-Americans, as a direct result of their African heritage, which means that the condition is significantly important for practitioners across the U. To understand. eferences Chowning, J. Washington State University Website. Frenette, P. And Atweh, G. References Chowning, J. Journal of Clinical Investigation, Ingram, V, sickle cell anemia essay.
Genetics, Nagel, R, sickle cell anemia essay. Encyclopedia of Life Sciences, John Wiley and Sons. Retrieved June 18,from:. Sickle Cell Anemia There are both advantages and disadvantages of having sickle cell anemia essay cell anemia.
How much benefit a person gets from sickle cell anemia's advantages, however, largely depends on where that person is located and what his or her environment is. The same concept applies to the disadvantages of this condition, although to a lesser extent, sickle cell anemia essay. The root of the advantages and disadvantages of this disease pertain to its specific form of anemia. Anemia is succinctly defined as an occurrence in a patient's blood characterized by a marked lack of healthy red blood cells.
Some of these blood cells look like a sickle because they are abnormally shaped. Because this disease is based on one's blood, it substantially impacts processes and conditions that are related to blood -- which has both boons and detriments. The principle boon associated with sickle cell anemia sickle cell anemia essay the fact that it has a selective…. Sickle Cell Rough Draft Sickle cell anemia is a blood disease that causes badly formed red blood cells.
The disease is genetec. Mostly people sickle cell anemia essay Africa or other coutries around the Mediterraean Sea get it. In the United States, African-Americans are most likely to have it Howard, Red blood cells are the blood cells that carry oxygen throughout the body.
When a person has sickle-cell anemia the hemoglobon in the cell is shaped wrong. ecause of this the cells are not round but sickle-shaped, which is how the disease gets its name. Sometimes these cells stick together and interfere with blood flow. This is very painful but also causes medical problems. It can cause damage to organs and sickle cell anemia essay the body from receiving the oxygen it needs to function well.
It also leaves the person likely to get lung infections Howard, Although sickle-cell anemia is genetec, both parents…, sickle cell anemia essay. Loupe, Diane E. If there is evidence of the sickle cell gene the tests will be repeated to confirm diagnosis NIH.
It is also possible to test the fetus for sickle cell anemia prior to birth through amniocentesis although this is not normally performed unless there is reason to believe the child will have sickle cell anemia due to the risk which this procedure presents to the fetus. Electrophoresis is performed on the blood to test for presence of the sickle cell gene as there are different patterns observed in those with sickle cell anemia than normal blood, as sickle cell anemia essay hemoglobin present is Hb S.
rather than the Hb a or Hb A2 which is usually present in normal adult erythrocytes or Hb F. which is usually present in fetal hemoglobin, sickle cell anemia essay. When the blood sample of a sickle cell sufferer is examined under the microscope, the sickle shaped cells present an immediate diagnosis….
References Sickle Cell Anemia. National Heart Lung and Blood Institute, National Institutes of Health. Sickle Cell Information: Clinician Summary, sickle cell anemia essay. Sickle Cell Information Centre. The science behind sickle cell anemia essay research was not incredibly profound, but again the article was fluidly written and very easy to follow the logic of.
Reflection: This is not an aspect of the disease I had thought of before; it is important to remember that there are very human bodies that contain these sickle-shaped cells. The fact that this "treatment" focuses on the sickle cell anemia essay of the disease rather than the cause is also indicative of the difficulty in combating the disease, sickle cell anemia essay.
Comfort is really all that's possible. Beutler, E. New York: Macmillan, pp. Retrieved via Gale Cengage. Summary: This encyclopedia entry gives a detailed overview of the disease -- it's pathology, causation, prevalence, etc. It begins with a definition of how the disease is classified, both through morphological changes to the red blood cells and, in more recent years, genetic…. relationship among African-Americans, Malaria and Sickle cell anemia.
Many people born in regions affected by malaria are resistant to the disease, sickle cell anemia essay. Malaria, rampant in parts of Africa, south of the Sahara has killed millions of people many of them little children. Further examination shows that those who are resistant to the disease carry at least one sickle cell trait. Blacks in America whose ancestors hail from Africa show a higher incidence of the disease. Are African-Americans who carry the abnormal gene proof of a genre of natural selection, allowing those with the trait to survive and those without the trait to perish?
I will explore the link between those with the sickle cell gene and their apparent immunity from malaria and the connection between African-Americans and their ancestors. What is Sickle Cell Anemia? Linus Pauling originally discovered sickle cell in Sickle cell anemia is a red blood cell disorder…. berkeley, edu Jared Diamond "Blood, Genes and Malaria. Healthcare has recently become a very polarizing and contentious issue within the United States, sickle cell anemia essay.
Healthcare expenditures as a percentage of GDP are currently percent. COVID has only exacerbated many of the prevailing trends surrounding healthcare and its subsequent treatment, sickle cell anemia essay. For one, the government has passed the affordable care act which attempts to lower healthcare costs through a series of legislative efforts. In addition, governments are attempting to redirect healthcare expenditures to focus primarily on outcomes as oppose to simply sickle cell anemia essay. This quality over quantity approach is very apparent when revieing sickle sickle cell anemia essay anemia and its overall complications.
Sickle Cell Anemia is actually a group of interrelated disorders that are often inherited at birth. Here, the disorder results from not having enough healthy red blood cells to….
References 1. Beutler, Ernest. Itano, Harvey A. and James V. Murayama, Makio and Robert Nalbandian. Sickle Cell Hemoglobin: Molecule to Man. Boston: Little, Brown and Company, This disease is a disorder of the blood brought by the inheritance of the gene that changes the shape of the sickle cell.
Understanding Sickle Cell Disease - Jumo Health
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Sickle cell anemia is an inherited blood disorder characterized primarily by chronic anemia and periodic episodes of pain. The underlying problem involves hemoglobin, a component of red blood cells. Hemoglobin molecules in each red blood cell carry oxygen from the lungs to body organs and tissues and bring carbon dioxide back to the lungs May 06, · Sickle cell anemia is a disorder of the blood that is caused by the inheritance of the gene that alters the shape of the sickle cell. Therefore, the gene interferes with the working of hemoglobin in the movement of oxygen. The prevalence of the sickle cell anemia varies regarding the geographical position and the ethnic identity Essay on Sickle Cell Anemia Words | 11 Pages. Abstract Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body. A gene causes the bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia
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